His talent as a flautist was appreciated within the noble circle of the House of Alba, where musical academies were held in which Misón actively participated and for which he composed 12 sonatas for transverse flute and bass dedicated to the Duke of Alba. These pieces were located in the archives of the House of Alba and described in 1927 by José Subirá (1882–1980), but unfortunately they disappeared during the Spanish Civil War (1936–39).

The discovery of the five hitherto unknown Sonatas for Flute and Bass by Misón represents a substantial contribution to the Spanish chamber music repertoire of the second third of the 18th century for this instrument, given the scarcity of pieces written by Hispanic composers contemporary to Misón in which the flute is definitely the real protagonist. Moreover, they are sonatas which, from a technical point of view, pose interesting challenges to the flautist, something that highlights Misón's mastery of the flute, in accordance with surviving documentation of the period. Ortega explains that José Teixidor (c.1751–c.1811), vice-master of the Royal Chapel from 1778, considered his works to be no lesser than those of the best-known foreign composers and said of him that he was an unequalled performer on the transverse flute. The sonatas are found in five musical manuscripts preserved in the Lebrija Palace in Seville, a stately home dating from the 16th century, which in 1901 became the property of Regla Manjón y Mergelina (1851–1938), Countess of Lebrija. With regard to the sources, it seems unlikely that any of the five are autograph. (Although up to five different copyists have been identified, there is nothing to suggest that any of them could be Misón, himself.)

Generally speaking, the sonatas are characterised by the importance of melody, regular phrases and steady rhythms, as can be seen in the elaborate seisillos of the Allegro moderato of the Sonata [no.3] in G major. Overall, the basso continuo line is simple – excepting the B section of the Allegro of the Sonata [no.4] in G major (undated) – allowing the role of the flute to stand out prominently.

This recording is the culmination of a long process of recovery of Spanish 18th-century musical heritage that deserves to be disseminated, studied and enhanced. After more than two centuries of silence, Misón's music is heard again.

Played on period instruments by flautist Rafael Ruibérriz de Torres, who studied with Wilbert Hazelzet and who played with Gustav Leonhardt, Philippe Herreweghe and Jos van Immerseel. The continuo is played by Isabel Gómez-Serranillos, cello, and Santiago Sampedro, harpsichord (on a double manual harpsichord after Flemish examples by Joop Klinkhamer).