During the sixteenth century in Italy, the motto ‘i galli cantano’ (the Gauls are singing) circulated, acknowledging the supremacy of the Franco-Flemish ‘transalpine’ musicians who were summoned to the peninsula to serve princes and prelates in the techniques of composing and performing vocal polyphony. Josquin Desprez, ‘Giosquino’ to the Italians, was the emblematic figure: in addition to France, he was in the service of Cardinal Ascanio Sforza in both Milan and Rome (1484, 1498) and of the papal (1489-95) and Este chapels (1503-4). On the fifth centenary of the composer’s death (1521), the Odhecaton ensemble proposes to retrace Josquin’s Italian itinerary with the Missa Hercules dux Ferrariæ, composed for the Duke of Ferrara Ercole I d’Este, and a selection of motets commissioned by Italian patrons. The contribution of The Gesualdo Six in the more solemn pieces brings the vocal ensemble to twenty-two singers, a number that is close to the forces of the Rome and Ferrara chapels and yields new sonic results in our quest to recreate how polyphony sounded in the fifteenth and early sixteenth centuries.