In a career spanning five decades, Sequeira Costa has developed his own musical interpretation from an understanding of the German and French schools, acquired through studies with his teacher, Vianna da Motta (one of the last pupils of Liszt and Hans von Bulow), Mark Hamburg, Edwin Fischer, Marguerite Long and Jacques Fevrier.

He has performed at the greatest halls around the world, including the Salle Gaveau and Salle Pleyel in Paris, the Great Hall of the Tchaikovsky Conservatory in Moscow, Tokyo's Suntori Hall, St Petersburg's Philharmonic Hall, the Vienna Musikverein, New York's Carnegie Hall, the Kennedy Center in Washington, D.C. and the major London halls.

He recently completed performances of the entire cycle of Beethoven Sonatas at Gulbenkian Hall in Lisbon, Portugal.